Yes, but EP Henry recommends that you wait at least 12 – 18 months before sealing to ensure that efflorescence has had a chance to come out. Depending upon the sealers, they can offer three advantages: they help resist stains, enhance the color, and bind the sand in the joints to make it difficult for weeds to germinate. Sealers, however, are topical products and must be reapplied regularly (generally every 3-5 years). Sealers maybe water-based or solvent-based as long as they are low VOC and compliant with government regulations.